Inhibitors of ergosterol biosynthesis as crop protection agents.

aneous and followed a reversible competitive mechanism in S/reptonivc~e.s p. and a reversible non-competitive mechanism in N . erythropo1i.s and S . wt t i t t i i t t i e . An irreversible type of inhibition was observed for 1'. lestostcrorii cholesterol oxid a se . T h e fit o f thc inhibition profile o f cyclic amines with cholesterol oxidases and AS A'-isomerases offers a fungicide screening system for agronomic and medical purposes. Fast and simple assays i , i iitro with microbial oxidases which arc readily available from commercial sources can be used. O n the other hand. inhibition of steroid nucleus breakdown by cyclic amines offers the possibility of improving the sidechain degradation process in biotcchnology. I I . Taton, M., Benvcnkte, P. di Kahier. A. ( I YX7) /+ i re App1. C ' / i i w i . 59.2X7-294 12. Woloshuk, C. P.. Sislcr. H. D. 6i Dulhy. S. K. ( I Y7Y) /tu//ittii ,roh.